Week 5 kicks off tonight with Thursday Night Football and an AFC South rivalry battling it out in prime time.

All records and facts courtesy of the NFL.

Indianapolis (2-2) @ Houston (1-3) - Indianapolis leads series 22-4. Last meeting was last season, Indianapolis won 17-10. Indianapolis is currently on a 5 game winning streak in the series.

Get your picks in now for our Pigskin Pickem Contest before the kickoff of the game tonight at 7:25.